Skip Navigation

ALS Alert Newsletter

field with sun shining

Oct 28
2021

Packard Center awards new research grant to investigate NEK1 haploinsufficiency in human motor neurons

The Packard Center has awarded a research grant to Evangelos Kiskinis, PhD for a project entitled: Investigating NEK1 haploinsufficiency in human motor neurons

The Packard Center is pleased to announce a grant to Evangelos Kiskinis, PhD of Northwestern University to investigate NEK1 haploinsufficiency in human motor neurons.

Mutations in the gene NEK1 are major contributors to ALS. The mechanisms by which these mutations impair the function of the NEK1 protein and cause the degeneration of motor neurons in ALS patients remain unclear. Dr. Kiskinis and his team are working to identify the molecular targets of NEK1 in human motor neurons and determine which ones mediate disease pathogenesis.