Oct 28
2021
Packard Center awards new research grant to investigate NEK1 haploinsufficiency in human motor neurons
The Packard Center has awarded a research grant to Evangelos Kiskinis, PhD for a project entitled: Investigating NEK1 haploinsufficiency in human motor neurons

The Packard Center is pleased to announce a grant to Evangelos Kiskinis, PhD of Northwestern University to investigate NEK1 haploinsufficiency in human motor neurons.
Mutations in the gene NEK1 are major contributors to ALS. The mechanisms by which these mutations impair the function of the NEK1 protein and cause the degeneration of motor neurons in ALS patients remain unclear. Dr. Kiskinis and his team are working to identify the molecular targets of NEK1 in human motor neurons and determine which ones mediate disease pathogenesis.
June 2021 Edition
- Packard Center awards new research grant to study new pathways of protein homeostasis in ALS
- Packard Center awards new research grant to investigate NEK1 haploinsufficiency in human motor neurons
- Packard Center awards new research grant to study the regulation of TDP-43 nuclear localization
- Packard Center awards new research grant to study unbiased lipid screening to reverse ALS Phenotypes in vitro and in vivo
- Virtual Fiesta 5K celebrates ALS Awareness Month
- Answer ALS annual symposium highlights promise and excitement
- Packard Center's 21st annual symposium held virtually with record attendance.
- Packard team identifies function of major ALS-linked protein
- Your donation will bring hope to those with ALS
- Packard Center awards new research grant to study proteogenomic identification of TDP-43-related splicing dysfunction in ALS/FTD.
- Packard Center awards new research grant to study the role of Vps4/ESCRT Complex in Nucleoporin Degradation in C9-ALS
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