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Clinical Trials

Clinical research is the only way to turn promising science into treatments. 

What is clinical research?

Clinical research is the only way to turn promising science into treatments for people. Learn more about the role of clinical research in the development of new treatments for people with motor neuron disease and how you can get involved.

Why is clinical research so important to finding a cure?

People with ALS who enroll in a clinical trial are contributing to improvein the lives of patients currently with the disease and fture generations. Even when the results of a trial are negative, researchers and clinicans learn that much more about the disease as well as how to look for more promising new treatments.

How to Find a Clinical Trial for ALS

The Northeast ALS Consortium (NEALS) provides up-to-date information for finding both federally and privately funded clinical studies focusing on ALS and motor neuron diseases. You can locate both interventional trials, which examine if treatments are effective and safe under controlled environments, and observation trials, which examine people in more natural environments.

To search the NEALS Clinical Trial Database, click here. 

Our Experts

Johns Hopkins University
Neurologist Charlotte Sumner has a long history of studying neuromuscular disorders. In particular, she has focused her attention on caring for patients with inherited motor neuron and peripheral nerve disorders such as spinal muscular atrophy and Charcot-Marie-Tooth disease. Her work on the molecular pathogenesis of spinal muscular atrophy and the development of therapeutics may provide important clues for those with ALS.

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University of Michigan
Sami Barmada wants to answer a very basic question about ALS: why motor neurons? Of all the different types of neurons in the body (and scientists estimate there are probably several hundred), it’s only motor neurons that are affected in ALS. Knowing why this is, Barmada believes, could be the key to developing new potential treatments that could prevent the deterioration and death of motor neurons. 
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